24677-78-9
Chemical Structure
2,3-Dihydroxybenzaldehyde
- CAS No.: 24677-78-9
- Formula:C7H6O3
- Molecular Weight:138.12
IUPAC Name: 2,3-dihydroxybenzaldehyde
InChIKey: IXWOUPGDGMCKGT-UHFFFAOYSA-N
SMILES: O=CC1=C(O)C(O)=CC=C1
Biological Activity: 2,3-Dihydroxybenzaldehyde is a derivative of Gentisaldehyde (HY-N1673), as well as an Antibacterial and anticancer agent. 2,3-Dihydroxybenzaldehyde inhibits the synthesis of DNA, RNA and proteins. It exhibits antibacterial activity against 172 Staphylococcus aureus isolates from bovine mastitis, with an MIC50 of 500 mg/L. 2,3-Dihydroxybenzaldehyde can be used in the research of bovine mastitis and L1210 mouse leukemia[1][2][3][4].
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2,3-Dihydroxybenzaldehyde | 99.62% | 2,3-Dihydroxybenzaldehyde is a derivative of Gentisaldehyde (HY-N1673), as well as an Antibacterial and anticancer agent. 2,3-Dihydroxybenzaldehyde inhibits the synthesis of DNA, RNA and proteins. It exhibits antibacterial activity against 172 Staphylococcus aureus isolates from bovine mastitis, with an MIC50 of 500 mg/L. 2,3-Dihydroxybenzaldehyde can be used in the research of bovine mastitis and L1210 mouse leukemia. | ||||||||||||||||||||
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- [1]. Tonde SS, et al. Self-activating nuclease activity of copper (II) complexes of hydroxyl-rich ligands. Journal of inorganic biochemistry. 2006 Jan;100(1):51-7. [Content Brief]
- [2]. Kato S, et al. Synthesis and biological activity of 4-amino-5-chloro-2-ethoxy-3-hydroxybenzamides, metabolites of a new gastroprokinetic agent, mosapride. Chemical & pharmaceutical bulletin. 1996 Aug;44(8):1484-92. [Content Brief]
- [3]. Schabauer A, et al. Gentisaldehyde and Its Derivative 2,3-Dihydroxybenzaldehyde Show Antimicrobial Activities Against Bovine Mastitis Staphylococcus aureus. Front Vet Sci. 2018 Jul 11;5:148. [Content Brief]
- [4]. Wick MM, et al. Antitumor effects of biologic reducing agents related to 3,4-dihydroxybenzylamine: dihydroxybenzaldehyde, dihydroxybenzaldoxime, and dihydroxybenzonitrile. Journal of pharmaceutical sciences. 1987 Jul;76(7):513-5. [Content Brief]
Keywords
