DBCO Phosphoramidite
DBCO Phosphoramidite is a phosphoramidite reagent containing a dibenzocyclooctyne (DBCO) moiety, which can introduce a strain-promoted alkyne group for copper-free click chemistry into DNA strands during solid-phase oligonucleotide synthesis. DBCO Phosphoramidite is applicable to studies related to oligonucleotide modification, copper-free click conjugation, and functionalized DNA nanomaterials.
For research use only. We do not sell to patients.
- Formula: C54H61N4O7P
- Molecular Weight:909.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
DBCO Phosphoramidite (0.1 M; 8-10 minutes) enables successful synthesis of folate-modified DNA strands via solid-phase synthesis, as verified by LC-MS analysis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 909.06
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Formula C54H61N4O7P
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SMILES
O=C(CCCCC(N1C(C=CC=C2)=C2C#CC(C=CC=C3)=C3C1)=O)NC(COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC)COP(N(C(C)C)C(C)C)OCCC#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)