HKOCl-4
Based on 2 publication(s) in Google Scholar
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity. HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm.
For research use only. We do not sell to patients.
- Purity: 95.05%
- CAS No.: 2031170-85-9
- Formula: C38H35Cl2NO7
- Molecular Weight:688.59
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) HKOCl-4
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Biological Activity
Ex: 530 nm; Em 557 nm
HKOCl-4 (10 μM) shows an increasing florescence intensity with increasing concentration of hypochlorous acid[1].HKOCl-4 exhibits a ultra-fast response towards 1 equiv of HOCl (reached a plateau within 2 min) , and it shows a >20-fold increase in fluorescence intensity over other analytes (1 equiv of OH and ONOO as well as 10 equiv of O2, NO, 1O2, ROO , TBHP and H2O2)[2].HKOCl-4 is first tested and it was proven to be non-toxic in living cells even at a concentration up to 50 μM in RAW264.7 macrophages[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
557
530
Chemical Information
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CAS No. 2031170-85-9
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Appearance Solid
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Molecular Weight 688.59
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Formula C38H35Cl2NO7
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Color Yellow to orange
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SMILES
O=C(OCC)CCCN1C(C)(C)CC(C)C2=C1C=C3C(C4(OC(C5=C4C=CC=C5)=O)C6=CC=C(OC7=CC(Cl)=C(O)C(Cl)=C7)C=C6O3)=C2
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Synonyms
BXY2142
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (2)
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Journal Impact Factor
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Most Recent
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J Nanobiotechnology
Heat shock protein 60-targeted peptide-conjugated platinum nanozyme: redox regulation by multi-enzyme activities induces mitochondrial reprogramming and acute leukemia cells fate switch. [Abstract]2026 May 26. PMID: 42192458 -
Biol Direct
2022 Sep 27;17(1):25. PMID: 36167556
Solvent & Solubility
DMSO : 200 mg/mL (290.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4522 mL | 7.2612 mL | 14.5224 mL | 36.3061 mL |
| 5 mM | 0.2904 mL | 1.4522 mL | 2.9045 mL | 7.2612 mL | |
| 10 mM | 0.1452 mL | 0.7261 mL | 1.4522 mL | 3.6306 mL | |
| 15 mM | 0.0968 mL | 0.4841 mL | 0.9682 mL | 2.4204 mL | |
| 20 mM | 0.0726 mL | 0.3631 mL | 0.7261 mL | 1.8153 mL | |
| 25 mM | 0.0581 mL | 0.2904 mL | 0.5809 mL | 1.4522 mL | |
| 30 mM | 0.0484 mL | 0.2420 mL | 0.4841 mL | 1.2102 mL | |
| 40 mM | 0.0363 mL | 0.1815 mL | 0.3631 mL | 0.9077 mL | |
| 50 mM | 0.0290 mL | 0.1452 mL | 0.2904 mL | 0.7261 mL | |
| 60 mM | 0.0242 mL | 0.1210 mL | 0.2420 mL | 0.6051 mL | |
| 80 mM | 0.0182 mL | 0.0908 mL | 0.1815 mL | 0.4538 mL | |
| 100 mM | 0.0145 mL | 0.0726 mL | 0.1452 mL | 0.3631 mL |
HKOCl-4 Related Classifications
HY-130027 Related Classifications
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