Srd5a3 - steroid 5 alpha-reductase 3 Gene

Also Known as H5ar; S5AR 3; Srd5a2l; A430076C09; 1110025P14Rik; D730040M03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57357

Summary

Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity and oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Involved in dolichol metabolic process; dolichol-linked oligosaccharide biosynthetic process; and polyprenol catabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in Kahrizi syndrome and congenital disorder of glycosylation Iq. Orthologous to human SRD5A3 (steroid 5 alpha-reductase 3). [provided by Alliance of Genome Resources, Apr 2022]

Srd5a3 Products (1)

mRNA Protein Name
NM_020611.4 NP_065636.2 polyprenol reductase

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in dolichol metabolic process IMP
IMP: Inferred from mutant phenotype
20637498 MGI
involved in dolichol-linked oligosaccharide biosynthetic process IMP
IMP: Inferred from mutant phenotype
20637498 MGI
involved in polyprenol catabolic process IMP
IMP: Inferred from mutant phenotype
20637498 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polyprenol reductase

  • 3-oxo-5-alpha-steroid 4-dehydrogenase 3

  • H5AR

  • SR type 3

  • probable polyprenol reductase

  • steroid 5 alpha-reductase 2 like

  • steroid 5 alpha-reductase 2-like

  • H5AR gene

  • steroid 5 alpha-reductase 2 like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS21945 Srd5a3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W010076 Methyl 2,4-dihydroxybenzoate Inhibitor 99.57% Unkown
HY-163938A PROTAC erf3a Degrader-2 / Unkown
HY-RS13756 SRD5A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28462 Srd5a3 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srd5a3 NCBI NCBI:79644