Rbm10 - RNA binding motif protein 10 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64510

Summary

Predicted to enable identical protein binding activity and miRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within negative regulation of RNA metabolic process; negative regulation of cell population proliferation; and positive regulation of smooth muscle cell apoptotic process. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in TARP syndrome. Orthologous to human RBM10 (RNA binding motif protein 10). [provided by Alliance of Genome Resources, Apr 2022]

Rbm10 Products (2)

mRNA Protein Name
NM_001414396.1 NP_001401325.1 RNA-binding protein 10 isoform 2
NM_152861.5 NP_690600.1 RNA-binding protein 10 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables single-stranded RNA binding IDA
IDA: Inferred from direct assay
8760884 RGD
Biological Process GO Annotation Evidence References Source
involved in cardiac muscle cell myoblast differentiation IEP
IEP: Inferred from expression pattern
24178303 RGD
involved in mRNA stabilization IMP
IMP: Inferred from mutant phenotype
19508861 RGD
involved in negative regulation of cell growth involved in cardiac muscle cell development IMP
IMP: Inferred from mutant phenotype
30257214 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
19508861 RGD
involved in positive regulation of execution phase of apoptosis IMP
IMP: Inferred from mutant phenotype
19508861 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding protein 10

  • RNA-binding protein S1-1

  • S1-1 protein from liver

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-142032 RBM10-8 Inhibitor / Unkown
HY-RS11731 RBM10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22768 Rbm10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29282 Rbm10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbm10 NCBI NCBI:8241