CRAC Channel Activator
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2-Aminoethyl diphenylborinate
(2-APB)
0 Images別名: 2-Aminoethyl diphenylborinate; 2-アミノエチル ジフェニルボリナート2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue.
