Antibacterial agent 182
Antibacterial agent 182 (compound 8c) is an antibacterial agent that shows antibacterial activity against various Gram-positive bacteria, particularly against Vancomycin-resistant Enterococcus faecalis (MIC ≤0.125 μg/mL). Antibacterial agent 182 inhibits biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa at sub-MIC doses.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C14H5Br4F3N2OS
- 分子量:625.88
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H1299 | IC50 |
8.25 μg/mL
Compound: 8c
|
Cytotoxicity against human NCI-H1299 cells measured after 72 hrs by SRB assay
Cytotoxicity against human NCI-H1299 cells measured after 72 hrs by SRB assay
|
[PMID: 38382392] |
| NCI-H1975 | IC50 |
4.4 μg/mL
Compound: 8c
|
Cytotoxicity against human NCI-H1975 cells measured after 72 hrs by SRB assay
Cytotoxicity against human NCI-H1975 cells measured after 72 hrs by SRB assay
|
[PMID: 38382392] |
化学情報
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分子量 625.88
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分子式 C14H5Br4F3N2OS
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SMILES
BrC(N1)=C(Br)C(Br)=C1C2=NC(C3=C(O)C(Br)=CC(C(F)(F)F)=C3)=CS2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)