Buforin II
Based on 1 Customer Validation
Buforin II, derived from buforin I, a protein isolated from the stomach of the Asian toad Bufo bufo gargarizans, is a potent antimicrobial peptide. Buforin II has antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.35%
- CAS 番号: 172998-24-2
- 分子式: C106H184N40O26
- 分子量:2434.85
-
保管条件:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
Buforin II inhibits A. baumanniiATCC 19606 and multiresistant strains with the similar MIC values of 8 mg/L[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Male Wistar rats weighing 200 to 300 g with A. baumannii ATCC 19606[1]
-
Dosage:1 mg/kg
-
Administration:Intravenously a single dose
-
Result:Reduced mortality by 40% in the treatment group and by 20% in the rifampicin (10 mg/kg) combination group.
Reduced TNF, IL-6 and endotoxin plasma levels by 33%, 25% and 32%, respectively.
-
Animal Model:Male Wistar rats weighing 200 to 300 g with the multiresistant strain[1]
-
Dosage:1 mg/kg
-
Administration:Intravenously a single dose
-
Result:Reduced mortality by 46.6% in the treatment group and by 20% in the rifampicin (10 mg/kg) combination group.
Reduced TNF, IL-6 and endotoxin plasma levels by 46%, 20% and 28%, respectively.
化学情報
-
CAS 番号 172998-24-2
-
性状 Solid
-
分子量 2434.85
-
分子式 C106H184N40O26
-
Color White to off-white
-
シーケンスの短縮
TRSSRAGLQFPVGRVHRLLRK
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
溶剤 & 溶解度
H2O : 100 mg/mL (41.07 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (269 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.4107 mL | 2.0535 mL | 4.1070 mL | 10.2676 mL |
| 5 mM | 0.0821 mL | 0.4107 mL | 0.8214 mL | 2.0535 mL | |
| 10 mM | 0.0411 mL | 0.2054 mL | 0.4107 mL | 1.0268 mL | |
| 15 mM | 0.0274 mL | 0.1369 mL | 0.2738 mL | 0.6845 mL | |
| 20 mM | 0.0205 mL | 0.1027 mL | 0.2054 mL | 0.5134 mL | |
| 25 mM | 0.0164 mL | 0.0821 mL | 0.1643 mL | 0.4107 mL | |
| 30 mM | 0.0137 mL | 0.0685 mL | 0.1369 mL | 0.3423 mL | |
| 40 mM | 0.0103 mL | 0.0513 mL | 0.1027 mL | 0.2567 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Buforin II 関連分類
HY-P1630 関連分類
Powered by Bioz