CK2-IN-15
CK2-IN-15 (Compound Biv5) is a selective and potent bivalent protein kinase CK2 inhibitor with an IC50 value of 51 pM. CK2-IN-15 significantly reduces the replication of SARS-CoV-2 in HEK-ACE2-TMPRSS2 and Vero cells, and also reduces viral replication in an ex vivo model of human nasal epithelial cells. CK2-IN-15 is promising for research of β-coronavirus infection-related diseases.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C34H35ClN4O2
- 分子量:567.12
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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CK2α 51 pM (IC50) |
化学情報
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分子量 567.12
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分子式 C34H35ClN4O2
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SMILES
O=C(C1=CC=C2C(N=C(NCCCCCCCCNCC3=CC=C(C4=CC=CC=C4)C(Cl)=C3)C5=C2C=NC=C5)=C1)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)