DNP Phosphoramidite
DNP Phosphoramidite is a non-nucleoside-based phosphoramidite carrying a 2,4-dinitrophenyl (DNP) hapten group, which enables multiple labeling of oligonucleotides during solid-phase synthesis. DNP Phosphoramidite binds to anti-DNP antibodies, allowing the detection of labeled oligonucleotides via enzyme-linked colorimetric techniques.
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- CAS 番号: 136949-85-4
- 分子式: C21H34N5O6P
- 分子量:483.50
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
DNP Phosphoramidite (0.15 M; 5 h deprotection, 30 mins detritylation) enables efficient solid-phase labelling of oligonucleotides, with "trityl-on" synthesis preventing degradation during 5-hour 60°C concentrated ammonia deprotection, and resulting labelled oligonucleotides showing increased lipophilicity for easy HPLC purification[1].
DNP Phosphoramidite enables DNP-labelled 24-mer oligonucleotides to exhibit optimal colorimetric dot blot detection sensitivity with 3 DNP labels, achieving limits comparable to biotin-labelled oligonucleotides regardless of spacer arm length[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 136949-85-4
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分子量 483.50
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分子式 C21H34N5O6P
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SMILES
CC(N(P(OCCC#N)OCCCCCCNC(C([N+]([O-])=O)=C1)=CC=C1[N+]([O-])=O)C(C)C)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DNP Phosphoramidite 関連分類
HY-W1061585 関連分類
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