DprE1-IN-5
DprE1-IN-5 (Compound 10) is a DprE1 inhibitor. DprE1-IN-5 has anti-TB activity against Mtb H37Rv strain (MIC: 4 μM). DprE1-IN-5 also has antimycobacterial activity against drug-resistant strains. DprE1-IN-5 has high microsomal stability.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3052383-46-4
- 分子式: C20H19N5O2
- 分子量:361.40
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| H9c2 | IC50 |
>50 μM
Compound: 10
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Cytotoxicity against rat H9c2 cells assessed as cell viability incubated for 72 hrs by MTT spectrophotometric analysis
Cytotoxicity against rat H9c2 cells assessed as cell viability incubated for 72 hrs by MTT spectrophotometric analysis
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[PMID: 37421887] |
| HepG2 | IC50 |
>125 μM
Compound: 10
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Cytotoxicity against human HepG2 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human HepG2 cells incubated for 24 hrs by MTT assay
|
[PMID: 37421887] |
| HepG2 | IC50 |
59.01 μM
Compound: 10
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Cytotoxicity against human HepG2 cells assessed as cell viability incubated for 72 hrs by MTT spectrophotometric analysis
Cytotoxicity against human HepG2 cells assessed as cell viability incubated for 72 hrs by MTT spectrophotometric analysis
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[PMID: 37421887] |
化学情報
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CAS 番号 3052383-46-4
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分子量 361.40
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分子式 C20H19N5O2
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SMILES
O=C1NC(N2CCOCC2)=NC3=C1N(CC4=CC=C5C=CC=CC5=C4)C=N3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DprE1-IN-5 関連分類
HY-155510 関連分類
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