Ccdc88a - coiled coil domain containing 88A Gene

Also Known as Ape; Giv; Grdn; Hkrp1; Girdin; A430106J12Rik; C130096N06Rik; C330012F17Rik; D130005J21Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 108686

Summary

Enables microtubule binding activity and protein kinase B binding activity. Involved in several processes, including TOR signaling; activation of protein kinase B activity; and regulation of DNA replication. Located in cell leading edge. Is expressed in several structures, including limb; lung; nervous system; sensory organ; and somite. Orthologous to human CCDC88A (coiled-coil domain containing 88A). [provided by Alliance of Genome Resources, Apr 2022]

Ccdc88a Products (3)

mRNA Protein Name
NM_001363368.1 NP_001350297.1 girdin isoform 1
NM_001363369.1 NP_001350298.1 girdin isoform 2
NM_176841.5 NP_789811.2 girdin isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables microtubule binding IDA
IDA: Inferred from direct assay
15882442 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19778506 MGI
enables protein kinase B binding IPI
IPI: Inferred from physical interaction
15753085 MGI
enables protein serine/threonine kinase activator activity IDA
IDA: Inferred from direct assay
15753085 MGI
Biological Process GO Annotation Evidence 参考文献 由来
involved in TOR signaling IDA
IDA: Inferred from direct assay
19778506 MGI
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: Inferred from direct assay
15753085 MGI
involved in regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15753085 MGI
involved in regulation of neuron projection development IDA
IDA: Inferred from direct assay
19778506 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in cell leading edge IDA
IDA: Inferred from direct assay
24211587 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

girdin

  • Akt-phosphorylation enhancer

  • Hook-related protein 1

  • coiled-coil domain-containing protein 88A

  • g alpha-interacting vesicle-associated protein

  • girders of actin filament

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS02061 CCDC88A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21994 Ccdc88a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28511 Ccdc88a Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Ccdc88a NCBI NCBI:55704