SGCZ - sarcoglycan zeta Gene

Also Known as ZSG1

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 137868

About SGCZ

Cytogenetic location: 8p22 Genomic coordinates (GRCh38): 8:14,084,845-15,238,431 (from NCBI)

This gene has 2 transcripts (splice variants), 247 orthologues and 2 paralogues. Low expression observed in reference dataset.

Summary

The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner Cytoskeleton and the extra-cellular matrix. [provided by RefSeq, Jul 2008]

SGCZ Products (4)

mRNA Protein Name
NM_001322879.2 NP_001309808.1 zeta-sarcoglycan isoform 2
NM_001322880.2 NP_001309809.1 zeta-sarcoglycan isoform 3
NM_001322881.2 NP_001309810.1 zeta-sarcoglycan isoform 4
NM_139167.4 NP_631906.2 zeta-sarcoglycan isoform 1

SGCZ Protein Structure

Sarcoglycan_1

Sarcoglycan_1: Sarcoglycan complex subunit protein (36 - 303)

  • 0
  • 100
  • 200
  • 312 a.a.
Protein Preferred Names Protein Names

zeta-sarcoglycan

  • zeta-SG

関連疾患

Diseases Alias
Hallucinogen Abuse
Dystonia 11, Myoclonic

  • Myoclonic Dystonia

  • Myoclonus-Dystonia Syndrome

  • DYT11

  • Myoclonic Dystonia 11

  • Alcohol-Responsive Dystonia

  • Myoclonus, Hereditary Essential

  • Dystonia-11, Myoclonic

  • Myoclonus-Dystonia

  • Dystonia 11

  • Hereditary Essential Myoclonus

  • Dystonia, Alcohol-Responsive

  • Dyt-Sgce

  • Dystonia, Alcohol Responsive

  • Dystonia-11

  • Dystonia, Myoclonic

  • Dystonia, Myoclonic, Type 11
Embryonal Testis Carcinoma

  • Testicular Embryonal Carcinoma

  • Embryonal Carcinoma Of Testis

  • Embryonal Carcinoma Of The Testis
Otopalatodigital Syndrome, Type Ii

  • Otopalatodigital Syndrome Type 2

  • Faciopalatoosseous Syndrome

  • OPD2

  • Opd Ii Syndrome

  • Opd Syndrome 2

  • Cranioorodigital Syndrome

  • Fpo

  • Oto-Palato-Digital Syndrome, Type Ii

  • Andre Syndrome

  • Oto-Palato-Digital Syndrome Type 2

  • Otopalatodigital Syndrome Type Ii

  • Cranio-Oro-Digital Syndrome

  • Opd 2 Syndrome

  • Opd Syndrome, Type 2

  • Taybi Syndrome

  • Otopalatodigital Syndrome 2

  • Oto-Palato-Digital Syndrome, Type 2

  • Oto-Palato-Digital Syndrome Type 1
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 2

  • Lgmd2b

  • Muscular Dystrophy, Limb-Girdle, Type 2b

  • Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2e

  • Beta-Sarcoglycanopathy

  • Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2y

  • Muscular Dystrophy, Limb-Girdle, Type 3

  • Lgmd3

  • Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2s

  • LGMDR2

  • Muscular Dystrophy, Limb-Girdle, Type 2s

  • Limb-Girdle Muscular Dystrophy Type 2b

  • Lgmd2e

  • Limb-Girdle Muscular Dystrophy Due To Beta-Sarcoglycan Deficiency

  • Muscular Dystrophy, Limb-Girdle, Type 2e

  • Lgmd2s

  • Autosomal Recessive Muscular Dystrophy Due To Lap1b Deficiency

  • Autosomal Recessive Muscular Dystrophy Due To Torsin-1a-Interacting Protein 1 Deficiency

  • Lgmd2y

  • Muscular Dystrophy With Progressive Weakness, Distal Contractures And Rigid Spine

  • Muscular Dystrophy, Limb-Girdle, Type 2y

  • Dysferlin-Related Limb-Girdle Muscular Dystrophy R2

  • Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2b

  • Dysferlin-Related Lgmd R2

  • Lgmd Due To Dysferlin Deficiency

  • Lgmd Type 2b

  • Limb-Girdle Muscular Dystrophy Due To Dysferlin Deficiency

  • Limb-Girdle Muscular Dystrophy 2b

  • Limb-Girdle Muscular Dystrophy, Type 2b

  • Dystrophy, Muscular, Limb-Girdle, Autosomal Recessive, Type 2

  • Dystrophy, Muscular, Limb-Girdle, Type 2b

  • Limb-Girdle Muscular Dystrophy, Type 2e
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS12795 SGCZ Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22322 Sgcz Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28844 Sgcz Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus SGCZ RGD RGD:1307788
Canis familiaris SGCZ VGNC VGNC:49686
Macaca mulatta SGCZ VGNC VGNC:77230
Felis catus SGCZ VGNC VGNC:107463
Mus musculus SGCZ MGD MGI:2388820
Others SGCZ NCBI