DCAF13 - DDB1 and CUL4 associated factor 13 Gene

Also Known as GM83; Sof1; WDSOF1; HSPC064

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 25879

About DCAF13

Cytogenetic location: 8q22.3 Genomic coordinates (GRCh38): 8:103,415,386-103,443,453 (from NCBI)

This gene has 10 transcripts (splice variants) and 216 orthologues. Ubiquitous expression in testis (RPKM 16.5), kidney (RPKM 11.1) and 25 other tissues.

Summary

Enables Estrogen receptor binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in several cellular components, including centrosome; cytosol; and nuclear lumen. Part of Cul4-RING E3 ubiquitin Ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

DCAF13 Products (1)

mRNA Protein Name
NM_015420.7 NP_056235.5 DDB1- and CUL4-associated factor 13

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables nuclear estrogen receptor binding IPI
IPI: Inferred from physical interaction
28068668 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
28068668 GOA
enables ubiquitin-like ligase-substrate adaptor activity IDA
IDA: Inferred from direct assay
30111536 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in decidualization IDA
IDA: Inferred from direct assay
35932979 GOA
involved in epigenetic programming in the zygotic pronuclei IDA
IDA: Inferred from direct assay
30111536 GOA
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
30111536 GOA
involved in spindle assembly involved in female meiosis IDA
IDA: Inferred from direct assay
31492966 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
part of Cul4-RING E3 ubiquitin ligase complex IDA
IDA: Inferred from direct assay
16949367 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
30111536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DCAF13 Protein Structure

WD40

WD40: WD domain, G-beta repeat (211 - 247)

WD40

WD40: WD domain, G-beta repeat (252 - 289)

WD40

WD40: WD domain, G-beta repeat (426 - 461)

WD40

WD40: WD domain, G-beta repeat (480 - 505)

Sof1

Sof1: Sof1-like domain (506 - 593)

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  • 200
  • 300
  • 400
  • 500
  • 597 a.a.
Protein Preferred Names Protein Names

DDB1- and CUL4-associated factor 13

  • WD repeat and SOF domain-containing protein 1

DCAF13 抗体

製品番号 製品名 アプリケーション 反応性
HY-P86844 DCAF13 Antibody (YA6537) WB, IHC-P, IP Human, Mouse, Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS03560 DCAF13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Mus musculus DCAF13 MGD MGI:2684929
Felis catus DCAF13 VGNC VGNC:81644
Rattus norvegicus DCAF13 RGD RGD:1308458
Bos taurus DCAF13 VGNC VGNC:53857
Canis familiaris DCAF13 VGNC VGNC:39791
Others DCAF13 NCBI