Dlx3 - distal-less homeobox 3 Gene

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in epithelial cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including odontoblast differentiation; odontogenesis of dentin-containing tooth; and placenta development. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 4 and trichodontoosseous syndrome. Orthologous to human DLX3 (distal-less homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]