TMEM163 - transmembrane protein 163 Gene

Also Known as DC29; SV31

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 81615

About TMEM163

Cytogenetic location: 2q21.3 Genomic coordinates (GRCh38): 2:134,455,759-134,719,000 (from NCBI)

This gene has 3 transcripts (splice variants) and 273 orthologues. Broad expression in lung (RPKM 2.2), brain (RPKM 1.9) and 15 other tissues.

Summary

Predicted to enable zinc ion binding activity. Predicted to be involved in zinc ion import into synaptic vesicle. Predicted to be located in early endosome membrane. Predicted to be active in intracellular vesicle and plasma membrane. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM163 Products (1)

mRNA Protein Name
NM_030923.5 NP_112185.1 transmembrane protein 163

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
25130899 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in myelination IMP
IMP: Inferred from mutant phenotype
35455965 GOA
involved in zinc export across plasma membrane IDA
IDA: Inferred from direct assay
31697912 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 163

TMEM163 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
TMEM163 Q8TC26 SLC30A3 Homo sapiens Q99726
Anti Tag CoIP
36204728
Intra
TMEM163 Q8TC26 SLC30A3 Homo sapiens Q99726
Confocal
36204728
Intra
TMEM163 Q8TC26 SLC30A1 Homo sapiens Q9Y6M5
Anti Tag CoIP
36204728
Intra
TMEM163 Q8TC26 SLC30A1 Homo sapiens Q9Y6M5
Confocal
36204728
Intra
TMEM163 Q8TC26 SLC30A4 Homo sapiens O14863
Anti Tag CoIP
36204728
Intra
TMEM163 Q8TC26 SLC30A4 Homo sapiens O14863
Confocal
36204728
Intra
TMEM163 Q8TC26 SLC30A2 Homo sapiens Q9BRI3
Confocal
36204728
Intra
TMEM163 Q8TC26 SLC30A2 Homo sapiens Q9BRI3
Anti Tag CoIP
36204728
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Retinitis Pigmentosa 3

  • RP3

  • Retinitis Pigmentosa 15

  • Rp15

  • Choroidoretinal Degeneration With Retinal Reflex In Heterozygous Women

  • Cone-Rod Degeneration, X-Linked

  • Retinitis Pigmentosa Type 15

  • X-Linked Cone-Rod Degeneration

  • X-Linked Retinitis Pigmentosa 3

  • Xlrp3

  • Xlrp-3

  • Retinitis Pigmentosa-3

  • Retinitis Pigmentosa, Type 3
Brachydactyly, Type A1

  • Brachydactyly Type A1

  • BDA1

  • Farabee-Type Brachydactyly

  • Farabee Type Brachydactyly

  • Brachydactyly Farabee Type

  • Brachydactyly, Farabee Type

  • Brachydactyly A1

  • Brachydactyly
Mucolipidosis Iv

  • Mucolipidosis Type Iv

  • ML4

  • Sialolipidosis

  • Mucolipidosis Type 4

  • Ganglioside Sialidase Deficiency

  • Mliv

  • Ml Iv

  • Berman Syndrome

  • Ganglioside Neuraminidase Deficiency

  • Ml 4

  • Mucolipidosis 4

  • Type Iv Mucolipidosis

  • Gangliosidoses
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS14677 TMEM163 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus TMEM163 VGNC VGNC:35988
Felis catus TMEM163 VGNC VGNC:107679
Mus musculus TMEM163 MGD MGI:1919410
Canis familiaris TMEM163 VGNC VGNC:49815
Rattus norvegicus TMEM163 RGD RGD:1306212
Macaca mulatta TMEM163 VGNC VGNC:104557
Others TMEM163 NCBI