ABHD14B - abhydrolase domain containing 14B Gene

Also Known as CIB; HEL-S-299

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 84836

About ABHD14B

This gene has 8 transcripts (splice variants), 208 orthologues and 12 paralogues. Ubiquitous expression in fat (RPKM 33.8), kidney (RPKM 32.8) and 25 other tissues.

Summary

Enables hydrolase activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ABHD14B Products (3)

mRNA Protein Name
NM_001146314.2 NP_001139786.1 putative protein-lysine deacylase ABHD14B isoform 1
NM_001254753.1 NP_001241682.1 putative protein-lysine deacylase ABHD14B isoform 3
NM_032750.3 NP_116139.1 putative protein-lysine deacylase ABHD14B isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables hydrolase activity IDA
IDA: Inferred from direct assay
14672934 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
14672934 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
14672934 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in cytosol IDA
IDA: Inferred from direct assay
14672934 GOA
located in nucleus IDA
IDA: Inferred from direct assay
14672934 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ABHD14B Protein Structure

Abhydrolase_5

Abhydrolase_5: Alpha/beta hydrolase family (35 - 188)

  • 0
  • 100
  • 200
  • 210 a.a.
Protein Preferred Names Protein Names

putative protein-lysine deacylase ABHD14B

  • CCG1-interacting factor B

Recombinant ABHD14B Proteins

製品番号 製品名 アクセッション番号 純度
HY-P76132 ABHD14B Protein, Human (His) Q96IU4-1 (M1-Q210) ≥ 95%, as determined by reducing SDS-PAGE.

関連疾患

Diseases Alias
Williams-Beuren Syndrome

  • Williams Syndrome

  • WBS

  • Wms

  • Deletion 7q11.23

  • Monosomy 7q11.23

  • Chromosome 7q11.23 Deletion Syndrome, 1.5- To 1.8-Mb

  • Fanconi Schlesinger Syndrome

  • Beuren Syndrome

  • Elfin Facies Syndrome

  • Elfin Facies With Hypercalcemia

  • Hypercalcemia-Supravalvar Aortic Stenosis

  • Ws
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS00088 ABHD14B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20206 Abhd14b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26711 Abhd14b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus ABHD14B RGD RGD:1359649
Bos taurus ABHD14B VGNC VGNC:25493
Mus musculus ABHD14B MGD MGI:1923741
Canis familiaris ABHD14B VGNC VGNC:37462
Felis catus ABHD14B VGNC VGNC:59479
Macaca mulatta ABHD14B VGNC VGNC:69541
Others ABHD14B NCBI