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United States

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製品番号: HY-180396

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Ikarisoside B

Ikarisoside B is a potent and selective Organic cation transporter 1 (OCT1) inhibitor with an IC₅₀ of 11.18 μM. Ikarisoside B shows selectivity over OCT2 (IC₅₀ = 56.54 μM). Ikarisoside B can be used for the research of metabolic disease.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 113558-10-4
分子式: C₃₂H₃₈O₁₅
分子量:662.64

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Ikarisoside B 構造式

CAS 番号: 113558-10-4

容量

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target^[1]

OCT1

11.18 μM (IC₅₀)

OCT2

56.54 μM (IC₅₀)

体外実験

Ikarisoside B (up to 250 μM; 12 h) shows no cytotoxicity in HEK-EV, HEK-OCT1 and HEK-OCT2 cells up to 250 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

HEK-EV, HEK-OCT1 and HEK-OCT2 cells
Concentration:

up to 250 μM
Incubation Time:

12 h
Result:

Exhibited no cytotoxicity in HEK-EV, HEK-OCT1 and HEK-OCT2 cells up to 250 μM, with cell viability > 90%.
Showed 100% cell survival rate in HEK-EV, HEK-OCT1 and HEK-OCT2 cells.

化学情報

CAS 番号 113558-10-4
分子量 662.64
分子式 C₃₂H₃₈O₁₅
SMILES

O(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2CC=C(C)C)C3=CC=C(O)C=C3)[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@@H](O)[C@H](C)O4
Structure Classification
- Flavonoids
- Flavonols
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (275 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Bi Y, et al. Selective Inhibition of Organic Cation Transporter 1 by Benzoylpaeoniflorin Attenuates Hepatic Lipid Accumulation through AMPK Activation. J Nat Prod. 2023;86(1):191-198. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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