Monardic acid A
Monardic acid A is a selective inhibitor of AChE, with an IC50 of 53.1 μM against AChE from electric eel. Monardic acid A shows weak inhibitory activity against human erythrocyte AChE (IC50 >100 μM) and has no significant inhibitory effect on BChE. Monardic acid A reduces acetylcholine breakdown by inhibiting AChE activity, and also exhibits inhibitory activity against histamine release and hyaluronidase, thus exerting anti-inflammatory and neurotransmitter regulatory effects. Monardic acid A can be isolated from lungwort (Pulmonaria officinalis) and thyme (Thymus gobicus), and is mainly used in the development of anti-inflammatory drugs and drugs related to neurodegenerative diseases.
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- CAS 番号: 1607436-76-9
- 分子式: C27H22O12
- 分子量:538.46
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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AChE |
化学情報
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CAS 番号 1607436-76-9
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分子量 538.46
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分子式 C27H22O12
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SMILES
OC([C@@H]1C2=C(/C=C/C(O[C@@H](C(O)=O)CC3=CC(O)=C(C=C3)O)=O)C=CC(O)=C2O[C@H]1C4=CC(O)=C(C=C4)O)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Monardic acid A 関連分類
HY-N16715 関連分類
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