P2X7-IN-2
Based on 1 publication(s) in Google Scholar
P2X7-IN-2 (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 can be used for the research of autoimmunity, inflammation and cardiovascular disease.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1058709-63-9
- 分子式: C22H21F4N3O2
- 分子量:435.41
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 P2X7-IN-2
MoreP2X Receptor アイソフォーム固有の製品をすべて表示
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生物活性
IC50: 0.01 nM (human whole blood IL-Iβ release)[1]
P2X7-IN-2 (0-1 μM;30 min) inhibits human whole blood IL-Iβ release with an IC50 value of 0.01 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1058709-63-9
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分子量 435.41
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分子式 C22H21F4N3O2
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SMILES
O=C(NC1=C(C)C=CC2=C1C=CN([C@H](C)CN)C2=O)CC3=CC=C(C(F)(F)F)C(F)=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Int Immunopharmacol
CGRP alleviates epilepsy via JAK1-STAT1-P2RX7 signaling: a novel neuroprotective axis targeting neuronal damage. [Abstract]2025 Dec 21:170:116080. PMID: 41429063
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
P2X7-IN-2 関連分類
HY-18725 関連分類
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