Plafibride hydrochloride
Plafibride hydrochloride (ITA 104 hydrochloride) is an orally active hypolipemic, platelet aggregation inhibitor.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 65285-81-6
- 分子式: C16H23Cl2N3O4
- 分子量:392.28
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Lipocalin Family アイソフォーム固有の製品をすべて表示
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生物活性
Plafibride hydrochloride has low toxicity, with LD50s of about 4000 mg/kg (p.o.) in rat, mouse and hamster[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rabbit[1]
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Dosage:100 mg/kg
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Administration:Oral administration (p.o.)
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Result:Induced platelet aggregation.
化学情報
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CAS 番号 65285-81-6
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分子量 392.28
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分子式 C16H23Cl2N3O4
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SMILES
O=C(NCN1CCOCC1)NC(C(C)(C)OC2=CC=C(C=C2)Cl)=O.Cl
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別名
ITA 104 hydrochloride
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. L Bruseghini, et al. Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit. Arzneimittelforschung. 1981;31(10a):1790-5. [Content Brief]
[2]. J Zapatero, et al. Toxicological studies of plafibride. Part 1: Acute toxicity and its determination after several administrations of plafibride. Arzneimittelforschung. 1981;31(10a):1816-9. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)