PGD Protein, Human (His)
PGD Protein is crucial in cellular metabolism, catalyzing the oxidative decarboxylation of 6-phosphogluconate. This process yields ribulose 5-phosphate, releases CO(2), and simultaneously reduces NADP to NADPH, contributing to essential cellular redox balance. The enzyme's functionality underscores its significance in maintaining cellular homeostasis and participating in key metabolic pathways. PGD Protein, Human (His) is the recombinant human-derived PGD protein, expressed by E. coli , with N-His labeled tag.
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- Species: Human
- Source: E. coli
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保管条件:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
生物活性
PGD Protein is crucial in cellular metabolism, catalyzing the oxidative decarboxylation of 6-phosphogluconate. This process yields ribulose 5-phosphate, releases CO(2), and simultaneously reduces NADP to NADPH, contributing to essential cellular redox balance. The enzyme's functionality underscores its significance in maintaining cellular homeostasis and participating in key metabolic pathways. PGD Protein, Human (His) is the recombinant human-derived PGD protein, expressed by E. coli , with N-His labeled tag.
PGD Protein plays a pivotal role in cellular metabolism by catalyzing the oxidative decarboxylation of 6-phosphogluconate, leading to the formation of ribulose 5-phosphate and the release of CO(2). This enzymatic process is coupled with the simultaneous reduction of NADP to NADPH, contributing to vital cellular redox balance. The functionality of PGD Protein in mediating these biochemical reactions underscores its significance in maintaining cellular homeostasis and participating in key metabolic pathways.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-His
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アクセッション番号
P52209-1 (M1-A483)
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遺伝子ID5226 [NCBI]
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Molecular Construction
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N-term
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His
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PGD (M1-A483)
Accession # P52209-1 -
C-term
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Protein Length
Full Length of Isoform-1
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別名
PGD; Phosphogluconate Dehydrogenase (NADP(+)-Dependent, Decarboxylating); Phosphogluconate Dehydrogenase; 6PGD; 6-Phosphogluconate Dehydrogenase, Decarboxylating; PGDH
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AA Sequence
MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA
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Predicted Molecular Mass
54.6 kDa
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分子量
Approximately 46 kDa, based on SDS-PAGE under reducing conditions.
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純度
≥ 85%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
ドキュメント
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)