Bencianol
Bencianol is a the semisynthetic flavinoid, with anti-spasmogenic activities.
For research use only. We do not sell to patients.
- CAS No.: 85443-48-7
- Formula: C28H22O6
- Molecular Weight:454.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Bencianol causes a dose-related (1-100 μg/mL) reversal of contractions induced by 5-hydroxytryptamine, nor-adrenaline, angiotensin II, prostaglandin F2a, and U-46619 (a thromboxane-A2 mimetic). Bencianol is more effective against contractions induced by EC50 compared to maximal concentrations of each agent, and is least effective against the thromboxane-A2 mimetic, U-46619[1]. Bencianol (0.1-100 nM) produces cytoprotective effects against CCl4 induced cell injury on the above three parameters[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 85443-48-7
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Molecular Weight 454.47
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Formula C28H22O6
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SMILES
O[C@@H]1[C@@H](C2=CC=C(OC(C3=CC=CC=C3)(C4=CC=CC=C4)O5)C5=C2)OC6=CC(O)=CC(O)=C6C1
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Synonyms
ZY15051
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Whalley ET, et al. Anti-spasmogenic effects of bencianol (ZY15051) on human cerebral arteries in vitro. Cephalalgia. 1985 Dec;5(4):217-21. [Content Brief]
[2]. Maignan MF, et al. Cytoprotective effects of Bencianol on porcine vascular endothelial cells in vitro. J Submicrosc Cytol. 1986 Jan;18(1):47-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)