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Cat. No.: HY-146398

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AMPK activator 6

AMPK activator 6 (Compound GC) reduces lipid content and activates the AMPK pathway in HepG2 and 3T3-L1 cells. AMPK activator 6 significantly suppresses the increase in triglyceride (TG) , total cholesterol (TC), low-density lipoprotein-C (LDL-C), and other biochemical indices in blood serum. AMPK activator 6 can be used for the research of non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome.

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CAS No.: 189299-03-4
화학식: C₂₅H₂₈O₅
분자량:408.49

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

AMPK activator 6 Chemical Structure

CAS No.: 189299-03-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
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Classifications
Bioz

Biological Activity

제품 설명

All AMPK Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	18.2 μM Compound: 3, 3'-geranylchalconaringenin	Cytotoxicity against human HeLa cells by MTT assay after 72 hrs Cytotoxicity against human HeLa cells by MTT assay after 72 hrs	[PMID: 18611049]

Chemical Information

CAS No. 189299-03-4
분자량 408.49
화학식 C₂₅H₂₈O₅
SMILES

C/C(C)=C\CC/C(C)=C\CC1=C(C=C(C(C(/C=C/C2=CC=C(C=C2)O)=O)=C1O)O)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mengdi Zhang, et al. Synthesis of natural 3'-Prenylchalconaringenin and biological evaluation of ameliorating non-alcoholic fatty liver disease and metabolic syndrome. Eur J Med Chem. 2020 Nov 1;205:112649. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
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순도&문서
References

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AMPK activator 6

All AMPK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

AMPK activator 6 Related Classifications

HY-146398 Related Classifications