3370-69-2
3370-69-2
Chemical Structure
1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione
- CAS No.: 3370-69-2
- Formula:C9H11BrN2O6
- Molecular Weight:323.10
IUPAC Name: 5-bromo-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: AGFIRQJZCNVMCW-MNCSTQPFSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@H](O)[C@H](N2C(NC(C(Br)=C2)=O)=O)O1
Biological Activity: 1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione | 1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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