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Etedesiran

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Etedesiran is a component of the AOC drug Delpacibart etedesiran (HY-177565), formed by the reaction of an siRNA that induces cleavage of mRNA encoding myotonic dystrophy protein kinase (MTPK or DMPK) with SMCC linker (HY-42360). Etedesiran carries a maleimide group at its terminus, which can react with cysteine or lysine and is used for the synthesis of AOC drugs. Etedesiran is applicable to research related to myotonic dystrophy type 1.

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  • Purity: 93.16%
  • 분자량:13699.70
  • 보관:

    -20°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Etedesiran Chemical Structure
    Etedesiran Chemical Structure
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주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
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  • Etedesiran Chemical Structure
    Etedesiran Chemical Structure RNA (Cm-sp-Cm-sp-Cm-Um-Am-Gm-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)C-Um-Gm-Um-Cm-Um-Um-Cm-Gm-sp-Am-sp-Am), 5′-[6-[[[4-[(3-mercapto-2,5-dioxo-1-pyrrolidinyl)methyl]cyclohexyl]carbonyl]amino]hexyl hydrogen phosphate], complex with RNA (Um-sp-(2′-deoxy-2′-fluoro)U-sp-Cm-Gm-Am-(2′-deoxy-2′-fluoro)A-Gm-Am-Cm-Am-Gm-Um-Um-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)A-Gm-Gm-Gm-sp-Um-sp-Um)
    1/16
  • RNA (Cm-sp-Cm-sp-Cm-Um-Am-Gm-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)C-Um-Gm-Um-Cm-Um-Um-Cm-Gm-sp-Am-sp-Am), 5′-[6-[[[4-[(3-mercapto-2,5-dioxo-1-pyrrolidinyl)methyl]cyclohexyl]carbonyl]amino]hexyl hydrogen phosphate], complex with RNA (Um-sp-(2′-deoxy-2′-fluoro)U-sp-Cm-Gm-Am-(2′-deoxy-2′-fluoro)A-Gm-Am-Cm-Am-Gm-Um-Um-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)A-Gm-Gm-Gm-sp-Um-sp-Um)