FGFR-IN-22
FGFR-IN-22 (Compound 23) is a FGFR inhibitor with IC50s of 0.631, 1.26, 0.851 and 1 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-22 effectively inhibits cell proliferation that depends on the FGFR1 and FGFR3 signaling pathway. FGFR-IN-22 can be used for cancers such as chronic lymphocytic leukemia (CLL) research.
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- CAS No.: 1431872-18-2
- 화학식: C23H21FN8O2
- 분자량:460.46
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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FGFR1 0.631 nM (IC50) |
FGFR2 1.26 nM (IC50) |
FGFR3 0.851 nM (IC50) |
FGFR4 1 nM (IC50) |
Chemical Information
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CAS No. 1431872-18-2
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분자량 460.46
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화학식 C23H21FN8O2
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SMILES
FC1=C(N(CC2=NC=CN2)C3=NC4=NC(C5=CN(C)N=C5)=CN=C4C=C3)C=C(OC)C=C1OC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)