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Cat. No.: HY-174993

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FHND5071 (1H)

FHND5071 (1H) is a selective inhibitor targeting the RET (rearrangement during transfection) tyrosine kinase. FHND5071 (1H) is promising for research of RET-driven cancers (such as thyroid cancer, lung cancer, etc.).

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CAS No.: 2493156-15-1
화학식: C₃₀H₃₃N₉O
분자량:535.64

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

FHND5071 (1H) Chemical Structure

CAS No.: 2493156-15-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

CAS No. 2493156-15-1
분자량 535.64
화학식 C₃₀H₃₃N₉O
SMILES

COC1=CC=C(C=N1)CN2C3CC2CN(C3)C4=NC=C(C=C4)C5=CC(N6CCN(CC6)C)=CN7N=CC(C#N)=C57
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang X, et al. Design and Discovery of Novel Selective RET Inhibitors with High Central Nervous System Penetration, Enhanced Pharmacokinetics, and Pharmacodynamics. J Med Chem. 2025 Jul 10;68(13):13990-14007. [Content Brief]

Calculators

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Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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