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Cat. No.: HY-175900

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FLT3 ligand-4

FLT3 ligand-4 (Intermediate of compound 35) is a FLT3 ligand that can be used to synthesize PROTAC degrader (HY-161280) targeting FLT3 degradation. FLT3 ligand-4 is applicable to research related to acute myeloid leukemia.

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CAS No.: 3031481-63-4
화학식: C₁₇H₁₃Cl₂N₅
분자량:358.22

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

FLT3 ligand-4 Chemical Structure

CAS No.: 3031481-63-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

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Chemical Information

CAS No. 3031481-63-4
분자량 358.22
화학식 C₁₇H₁₃Cl₂N₅
SMILES

NC1=NNC(C2=CC(N(CC3=C(Cl)C=CC=C3Cl)C=N4)=C4C=C2)=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Wang Z, et al.. Discovery of FLT3-targeting PROTACs with potent antiproliferative activity against acute myeloid leukemia cells harboring FLT3 mutations. European journal of medicinal chemistry. 2024 Mar 15;268:116237. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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