Uba2 - ubiquitin-like modifier activating enzyme 2 Gene

Also Known as Arx; Sae2; UBA1; Ubl1a2; Uble1b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50995

Summary

Enables SUMO activating enzyme activity. Predicted to be involved in positive regulation of protein sumoylation and protein sumoylation. Predicted to be located in nucleoplasm. Predicted to be part of SUMO activating enzyme complex. Predicted to be active in cytoplasm. Is expressed in branchial arch; embryo; limb; and neural fold. Orthologous to human UBA2 (ubiquitin like modifier activating enzyme 2). [provided by Alliance of Genome Resources, Apr 2022]

Uba2 Products (1)

mRNA Protein Name
NM_016682.2 NP_057891.1 SUMO-activating enzyme subunit 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables SUMO activating enzyme activity IDA
IDA: Inferred from direct assay
21554500 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15767674 MGI
enables transcription factor binding IPI
IPI: Inferred from physical interaction
15767674 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SUMO-activating enzyme subunit 2

  • SUMO1 activating enzyme subunit 2

  • Sumo-1 activating enzyme subunit 2

  • anthracycline-associated resistance ARX

  • ubiquitin-like 1 (sentrin) activating enzyme E1B

  • ubiquitin-like 1 (sentrin) activating enzyme subunit 2

  • ubiquitin-like 1-activating enzyme E1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-181772 MCULE-3064932370 Inhibitor / Unkown
HY-RS15320 UBA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19646 Uba2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26139 Uba2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uba2 NCBI NCBI:10054