L-Histidine buffer,Sterile
Based on 1 Customer Validation
L-Histidine buffer, Sterile is a commonly used antibody storage buffer.
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- Purity: 99.0%
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보관:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
The core of L-Histidine buffer, Sterile, is L-histidine, an essential basic amino acid for the human body. As a buffer, L-histidine has unique advantages: 1. Excellent buffering capacity: Its imidazole group on the side chain has a pKa value of approximately 6.0, giving it extremely strong buffering capacity within the physiologically relevant pH range of 5.5-6.5. 2. Multiple stabilizing functions: In addition to maintaining pH stability, histidine can also act as a stabilizer, antioxidant, and lyophilization protectant for proteins (especially monoclonal antibodies). It can interact directly with antibody proteins through various complex mechanisms, helping them maintain structural integrity and functional activity during storage and transportation.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[L-Histidine buffer,Sterile]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
순도&문서
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Data Sheet (237 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)