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Cat. No.: HY-50898S5

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Lapatinib-¹³C,d₇

(Synonyms: GW572016-¹³C,d₇; GW2016-¹³C,d₇)

Lapatinib-¹³C,d₇ (GW572016-¹³C,d₇) is the deuterium and ¹³C-labeled Lapatinib (HY-50898). Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1210608-87-9
화학식: C₂₈¹³CH₁₉D₇ClFN₄O₄S
분자량:589.09

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lapatinib-¹³C,d₇ Chemical Structure

CAS No.: 1210608-87-9

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Biological Activity
- 제품 설명
- In Vitro
- 신청
Chemical Information
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Biological Activity

제품 설명

All EGFR Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

신청

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1210608-87-9
Unlabeled Cas 231277-92-2
분자량 589.09
화학식 C₂₈¹³CH₁₉D₇ClFN₄O₄S
SMILES

[2H][13C]([2H])([2H])S(C([2H])([2H])C([2H])([2H])NCC1=CC=C(O1)C2=CC(C(NC3=CC(Cl)=C(C=C3)OCC4=CC(F)=CC=C4)=NC=N5)=C5C=C2)(=O)=O
Synonyms

GW572016-¹³C,d₇; GW2016-¹³C,d₇
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.