Lepunafusp alfa
Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2396411-71-3
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
fused with Homo sapiens IDUA (iduronidase, alpha-L-) isoform 1, Pr27-653 (1:2)
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
-
F(ab')2-G1-kappa
ELISA, FACS, Functional assay
Chemical Information
-
CAS No. 2396411-71-3
-
SMILES
[Lepunafusp alfa]
-
Synonyms
JR-171
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)