country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-126758

Copy Link Print Information

Ludartin

Ludartin a sesquiterpene lactone, which can be isolated from the plant Artemisia carruthii Wood. Ludartin reduces the expression of myeloperoxidase and malondialdehyde, enhances the expression of glutathione and superoxide dismutase in spinal cord tissue. Ludartin inhibits neuronal apoptosis. Ludartin inhibits the upregulation of tumor necrosis factor-α, interleukin-1β, and interleukin-6. Ludartin improves the motor function of rats with spinal cord injury.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 36149-87-8
화학식: C₁₅H₁₈O₃
분자량:246.30

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Ludartin Chemical Structure

CAS No.: 36149-87-8

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Glutathione Peroxidase Isoforms :

GPX1
GPX4

Cellular Effect

Cell Line	Type	Value	Description	References
A-431	IC₅₀	19 μM Compound: Ludartin	Cytotoxicity against human A431 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against human A431 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 31784199]
A549	IC₅₀	25.18 μM Compound: Ludartin	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31784199]
A549	IC₅₀	7.4 μM Compound: 1	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by sulphorhodamine B assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by sulphorhodamine B assay	[PMID: 23886685]
A549	IC₅₀	7.4 μM Compound: 1	Cytotoxicity against human A549 cells assessed as growth inhibition by colorimetric sulphorhodamine B assay Cytotoxicity against human A549 cells assessed as growth inhibition by colorimetric sulphorhodamine B assay	[PMID: 24484897]
B16-F10	IC₅₀	6.6 μM Compound: Ludartin	Cytotoxicity against mouse B16F10 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against mouse B16F10 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 31784199]
BHY	IC₅₀	25.18 μM Compound: Ludartin	Antiproliferative activity against human BHY cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human BHY cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31784199]
COLO 205	IC₅₀	25.18 μM Compound: Ludartin	Antiproliferative activity against human COLO205 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human COLO205 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31784199]
HCT-116	IC₅₀	6.9 μM Compound: 1	Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by sulphorhodamine B assay Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by sulphorhodamine B assay	[PMID: 23886685]
HCT-116	IC₅₀	6.9 μM Compound: 1	Cytotoxicity against human HCT116 cells assessed as growth inhibition by colorimetric sulphorhodamine B assay Cytotoxicity against human HCT116 cells assessed as growth inhibition by colorimetric sulphorhodamine B assay	[PMID: 24484897]
MCF7	IC₅₀	0.5 μM Compound: 1	Cytotoxicity against human MCF7 cells assessed as growth inhibition by colorimetric sulphorhodamine B assay Cytotoxicity against human MCF7 cells assessed as growth inhibition by colorimetric sulphorhodamine B assay	[PMID: 24484897]
MCF7	IC₅₀	25.18 μM Compound: Ludartin	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31784199]
MIA PaCa-2	IC₅₀	25.18 μM Compound: Ludartin	Antiproliferative activity against human MIAPaCa2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human MIAPaCa2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31784199]
PC-3	IC₅₀	7.5 μM Compound: 1	Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by sulphorhodamine B assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by sulphorhodamine B assay	[PMID: 23886685]
PC-3	IC₅₀	7.5 μM Compound: 1	Cytotoxicity against human PC3 cells assessed as growth inhibition by colorimetric sulphorhodamine B assay Cytotoxicity against human PC3 cells assessed as growth inhibition by colorimetric sulphorhodamine B assay	[PMID: 24484897]
T98G	IC₅₀	6.3 μM Compound: 1	Cytotoxicity against human T98G cells assessed as growth inhibition by colorimetric sulphorhodamine B assay Cytotoxicity against human T98G cells assessed as growth inhibition by colorimetric sulphorhodamine B assay	[PMID: 24484897]
THP-1	IC₅₀	3.1 μM Compound: 1	Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by sulphorhodamine B assay Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by sulphorhodamine B assay	[PMID: 23886685]
THP-1	IC₅₀	3.1 μM Compound: 1	Cytotoxicity against human THP1 cells assessed as growth inhibition by colorimetric sulphorhodamine B assay Cytotoxicity against human THP1 cells assessed as growth inhibition by colorimetric sulphorhodamine B assay	[PMID: 24484897]

Chemical Information

CAS No. 36149-87-8
분자량 246.30
화학식 C₁₅H₁₈O₃
SMILES

C[C@]12[C@]3([H])[C@]4([H])[C@](CCC(C)=C3C[C@@]1([H])O2)([H])C(C(O4)=O)=C
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xu Wei, et al., Ludartin exhibits therapeutic effect on spinal cord injury through inhibition of apoptosis and inflammation[J]. 2019.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

Ludartin

All Glutathione Peroxidase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Ludartin Related Classifications

HY-126758 Related Classifications