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Cat. No.: HY-110135R

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NBI-31772 (Standard)

NBI-31772 (Standard) is the analytical standard of NBI-31772. This product is intended for research and analytical applications. NBI-31772 is a non-selective IGFBP inhibitor (Ki=47 nM). NBI-31772 has neuroprotective effects and reduces infarct volume during cerebral ischemia. NBI-31772 can also restore or enhance proteoglycan synthesis in osteoarticular chondrocytes. In addition, NBI-31772 also increases the effect of IGF3 on zebrafish oocyte maturation.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 374620-70-9
화학식: C₁₇H₁₁NO₇
분자량:341.27

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

NBI-31772 (Standard) Chemical Structure

CAS No.: 374620-70-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information

Information

신청

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 374620-70-9
분자량 341.27
화학식 C₁₇H₁₁NO₇
SMILES

O=C(C1=CC(O)=C(O)C=C1)C2=NC(C(O)=O)=CC3=C2C=C(O)C(O)=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Khawaja XZ. Development of a scintillation proximity assay for human insulin-like growth factor-binding protein 4 compatible with inhibitor high-throughput screening. Anal Biochem. 2007;366(1):80-86. [Content Brief]

[2]. Mackay K B, et al. Neuroprotective effects of insulin-like growth factor-binding protein ligand inhibitors in vitro and in vivo[J]. Journal of Cerebral Blood Flow & Metabolism, 2003, 23(10): 1160-1167. [Content Brief]

[3]. De Ceuninck F, et al. Pharmacological disruption of insulin-like growth factor 1 binding to IGF-binding proteins restores anabolic responses in human osteoarthritic chondrocytes[J]. Arthritis Res Ther, 2004, 6: 1-11. [Content Brief]

[4]. Li J, et al. Insulin-like growth factor binding proteins inhibit oocyte maturation of zebrafish[J]. General and Comparative Endocrinology, 2019, 281: 83-90. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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