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Cat. No.: HY-132888

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NCATS-SM4487

NCATS-SM4487 is a highly selective unique dihydropyrimidine inhibitor against GALK1, with an IC₅₀ value of 0.05 μM.

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CAS No.: 2733617-81-5
화학식: C₂₅H₂₄ClFN₈O₂
분자량:522.96

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

NCATS-SM4487 Chemical Structure

CAS No.: 2733617-81-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

NCATS-SM4487 is a highly selective unique dihydropyrimidine inhibitor against GALK1, with an IC₅₀ value of 0.05 μM.

Chemical Information

CAS No. 2733617-81-5
분자량 522.96
화학식 C₂₅H₂₄ClFN₈O₂
SMILES

CN1C=C(C=N1)CNC(C2=C(NC(NC3=NC4=C(C(N)=C(C=C4)F)O3)=NC2C5=C(C=C(C=C5)C)Cl)C)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liu L, et al. Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J Med Chem. 2021 Sep 23;64(18):13551-13571. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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