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Cat. No.: HY-174144

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RJG-2036

RJG-2036 is a potent covalent inhibitor of human prostaglandin reductase 2 (PTGR2)(IC₅₀=100 nM). RJG-2036 inhibits NADPH-dependent reduction, significantly reducing secretion of proinflammatory cytokines like TNF-α and multiple eicosanoids in LPS-stimulated THP-1 macrophages. RJG-2036 is promising for research of inflammatory diseases.

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CAS No.: 2851993-73-0
화학식: C₂₀H₂₁N₅O₄S
분자량:427.48

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

RJG-2036 Chemical Structure

CAS No.: 2851993-73-0

사이즈

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Prostaglandin Receptor Isoforms :

Chemical Information

CAS No. 2851993-73-0
분자량 427.48
화학식 C₂₀H₂₁N₅O₄S
SMILES

O=C(N1CCN(CC1)C2=C(OC)C=CC=C2)C3=CC=CC(S(=O)(N4N=CN=C4)=O)=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Founds MW, et al. Human PTGR2 Inactivation Alters Eicosanoid Metabolism and Cytokine Response of Inflammatory Macrophages. ACS Chem Biol. 2025 May 19. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

농도 희석 계산기

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Concentration _(start) Concentration _(start)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

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RJG-2036

All Prostaglandin Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

RJG-2036 Related Classifications

HY-174144 Related Classifications