SDZ-FOX-988
SDZ-FOX-988 (FOX-988) is an orally active antidiabetic agent. SDZ-FOX-988 sequesters mitochondrial coenzyme A to inhibit carnitine palmitoyltransferase II. SDZ-FOX-988 induces mitochondrial injury. SDZ-FOX-988 causes a decrease in serum β-hydroxybutyrate or glucose. SDZ-FOX-988 can be used in the research of type 2 diabetes.
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- CAS No.: 139681-18-8
- 화학식: C25H29NO5
- 분자량:423.50
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 139681-18-8
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분자량 423.50
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화학식 C25H29NO5
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SMILES
O=C(C(C)(C)C)C1=CC=C(/C(OC(C2=CC=C(C(C(C)(C)C)=O)C=C2)=O)=N\OC)C=C1
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Synonyms
FOX-988
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Lau DT, et al. The effect of the fat content of food on the pharmacokinetics and pharmacodynamics of SDZ FOX 988, an antidiabetic agent, in the dog. Biopharm Drug Dispos. 1995 Mar;16(2):137-50. [Content Brief]
[2]. Vickers AE, et al. Consequences of mitochondrial injury induced by pharmaceutical fatty acid oxidation inhibitors is characterized in human and rat liver slices. Toxicol In Vitro. 2006 Oct;20(7):1173-82. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SDZ-FOX-988 Related Classifications
HY-19150 Related Classifications
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