Transcriptome analysis of rat kidney cells continuously exposed to cadmium using DNA microarray

  • J Toxicol Sci. 2007 Feb;32(1):103-5. doi: 10.2131/jts.32.103.
Ken-ichi Ohba  1 ,  Youhei Okawa ,  Yuki Matsumoto ,  Yasuhiro Nakamura ,  Hisayoshi Ohta
Affiliations
  • 1. Department of Health Administration, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa 228-8555, Japan. [email protected]
PMID: 17327699 DOI: 10.2131/jts.32.103
Abstract

To examine the transcriptional responses of rat kidney cells continuously exposed to cadmium, we performed DNA microarray analysis. Cadmium increased levels of expression of 27 genes, including genes for MT1, MT2, GSTa3 and B2m and reduced those of 4 genes.