1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. ML418

ML418 

Cat. No.: HY-122697
Handling Instructions

ML418 is the first potent, selective and CNS penetrating blocker of Kir7.1 potassium channel (IC50, 310 nM), which also potently inhibits Kir6.2/SUR1, and exhibits superior selectivity over other Kir channels.

For research use only. We do not sell to patients.

ML418 Chemical Structure

ML418 Chemical Structure

CAS No. : 1928763-08-9

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Description

ML418 is the first potent, selective and CNS penetrating blocker of Kir7.1 potassium channel (IC50, 310 nM), which also potently inhibits Kir6.2/SUR1, and exhibits superior selectivity over other Kir channels[1].

Molecular Weight

377.87

Formula

C₁₉H₂₄ClN₃O₃

CAS No.

1928763-08-9

SMILES

O=C(OC(C)C)NC1CCN(CC2=CC(Cl)=C3C=CC=NC3=C2O)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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