Azaleucine
Azaleucine is an inhibitor of leucyl-tRNA synthetase. Azaleucine acts as an alternative substrate for this enzyme, undergoes pyrophosphate exchange reaction, and competes with leucine for the active site of the enzyme.
For research use only. We do not sell to patients.
- CAS No.: 4746-36-5
- Formula: C5H12N2O2
- Molecular Weight:132.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
DL-azaleucine (10 mM) serves as an alternative substrate for leucyl-tRNA synthetase from Aesculus hippocastanum cotyledons, supporting 20% of the pyrophosphate exchange activity seen with leucine at a concentration of 10 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4746-36-5
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Molecular Weight 132.16
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Formula C5H12N2O2
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SMILES
O=C(O)C(N)CN(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)