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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
cap-analog
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "cap-analog" in MCE Product Catalog:
Synonyms: m7G(5')ppp(5')(2'OMeA)pG ammonium
Cat. No.: HY-174497
eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.
Cat. No.: HY-141472
CAS No.: 104809-16-7
Synonyms: 7-Methyl-GDP sodium; m7GDP sodium
Target:
Synonyms: m7GpppA diammonium; N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
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m7G(5')ppp(5')A (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription .
Cat. No.: HY-153108
Purity: 99.62%
Synonyms: ARCA cap solution (100 mM)
Cat. No.: HY-145969
CAS No.: 1093268-63-3
Synonyms: 3'-O-Me-m7G(5')ppp(5')G
Research Areas:
β-S-ARCA (3'-O-Me-m7G(5')ppp(5')G) is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. β-S-ARCA binds eIF4E via electrostatic interactions between its β-sulfur atom and positively charged Arg and Lys residues in the protein binding site. β-S-ARCA prevents the decapping by Dcp2, increases the mRNA half-life, enhances cap-dependent translation, and increases protein expression in cells. β-S-ARCA has been applied in researching experimental mRNA-based anticancer vaccines .
Cat. No.: HY-145969A
Purity: 99.48%
Synonyms: 3’-O-Me-m7G(5')ppp(5')G triammonium
Research Areas:
β-S-ARCA (3'-O-Me-m7G(5')ppp(5')G) triammonium is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. β-S-ARCA triammonium binds eIF4E via electrostatic interactions between its β-sulfur atom and positively charged Arg and Lys residues in the protein binding site. β-S-ARCA triammonium prevents the decapping by Dcp2, increases the mRNA half-life, enhances cap-dependent translation, and increases protein expression in cells. β-S-ARCA triammonium has been applied in researching experimental mRNA-based anticancer vaccines .
Cat. No.: HY-158772
Purity: 99.6%
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m7G(5')ppp(5')(2'OMeA)pU ammonium is a cap analog that can be used for in vitro transcription of mRNA.
Cat. No.: HY-139101A
Purity: 99.97%
Synonyms: GpppA triammonium
Research Areas:
Guanosine 5'-triphosphate-5'-adenosine (GpppA) triammonium, a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine triammonium is a fluorescent substrate analog .
Cat. No.: HY-145977A
Synonyms: m7G(5')ppp(5')(2'OMeG)pG ammonium
Cat. No.: HY-145975A
Purity: 98.84%
Cat. No.: HY-145974
CAS No.: 62858-30-4
Synonyms: m7G(5')ppp(5')(2'OMeA)pG
Research Areas:
m7GpppAmpG (m7G(5')ppp(5')(2'OMeA)pG) is a trinucleotide 5′ cap analog. m7GpppAmpG binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG caps RNA with an efficiency of 90% and enhances mRNA stability and translation efficiency. m7GpppAmpG is used in mRNA therapeutic research .
Cat. No.: HY-145977
CAS No.: 1258049-00-1
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m7GpppGmpG is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86% .
Cat. No.: HY-145976
CAS No.: 133608-76-1
Research Areas:
m7GpppGpG is an unmodified trinucleotide cap analog with enhancer activity. When incorporated into mRNA, it effectively enhances translational efficiency, stability, and protein expression levels of the mRNA. m7GpppGpG can serve as a standard cap analog for in vitro mRNA synthesis to support antigen generation and presentation by dendritic cells, although its expression efficiency in dendritic cells is 20-fold lower than that of the m7GpppApG cap .
Cat. No.: HY-139100
CAS No.: 62828-63-1
Synonyms: m7GpppA
Cat. No.: HY-139101
CAS No.: 10527-47-6
Synonyms: GpppA
Cat. No.: HY-178672
CAS No.: 400806-46-4
Synonyms: Anti-Reverse cap analog; m2 7,3′O GpppG
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ARCA (Anti-Reverse cap analog) is a 5′- cap analogue. ARCA caps mRNA. ARCA can be used in protein expression studies .
Cat. No.: HY-145913
CAS No.: 80010-97-5
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m7GpppApG is a trinucleotide mRNA 5' cap analog that can be used for RNA synthesis in vitro .
Cat. No.: HY-158819
CAS No.: 2956651-00-4
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m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG trisodium is a cap analog that can be used for in vitro transcription of mRNA.
Cat. No.: HY-145913A
Purity: 99.28%
Target:
Research Areas:
m7GpppApG triammonium is a trinucleotide mRNA 5' cap analog that can be used for RNA synthesis in vitro .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
