14 Results for "

cxcr5

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "cxcr5" in MCE Product Catalog:

  • Targets Recommended:
4
4 Cited Publications
Cat. No.: HY-122197
CAS No.: 2579689-83-9
Purity:  99.88%
Research Areas:  

Cancer

ML339 is a selective CXCR6 antagonist with an IC50 of 140 nM. ML339 antagonizes β-arrestin recruitment and cAMP signaling pathway of human CXCR6 receptor induced by CXCL16, with IC50 of 0.3 μM and 1.4 μM, respectively. ML339 shows weaker activity against the recruitment of β-arrestin in mouse CXCR6 receptors, with an IC50 of 18 μM. ML339 has no inhibitory effect on CXCR5CXCR4CXCR6 and apelin receptor (APJ), with IC50 >79 μM. ML339 has the potential to promote the development of prostate cancer research .
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Cat. No.: HY-P991567
Synonyms: VX5/5261

Target:  

CXCR

Research Areas:  

Inflammation/Immunology Cancer

VX5 (VX5/5261) is a humanized IgG1κ monoclonal antibody inhibitor targeting BCA-1/CXCL13. VX5 significantly inhibits human CXCL13-mediated internalization of CXCR5, blocks both human and mouse CXCL13-dependent B-cells chemotaxis and migration. VX5 can be used to study autoimmune diseases like multiple sclerosis and arthritis, and cancers like gastric lymphomas and colon cancer .
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Cat. No.: HY-163480
CAS No.: 2796997-12-9

Target:  

CXCR

Research Areas:  

Inflammation/Immunology

PF-06835375 is a selective, humanized CXCR5-targeting immunoglobulin G1 antibody. PF-06835375 depletes CXCR5-positive B cells, follicular helper T cells and circulating Tfh-like cells. PF-06835375 is applicable to research related to autoimmune diseases .
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Cat. No.: HY-RS16995
Research Areas:  

Others

Cxcr5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cxcr5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174724
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CXCR5 mRNA encodes the human C-X-C motif chemokine receptor 5 (CXCR5) protein, a multi-pass membrane protein that belongs to the CXC chemokine receptor family. CXCR5 is involved in B-cell migration into B-cell follicles of spleen and Peyer patches.
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Cat. No.: HY-RS03409
Research Areas:  

Others

CXCR5 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCR5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23438
Research Areas:  

Others

Cxcr5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cxcr5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991227
Synonyms: BAY-924 antibody

Target:  

CXCR

Research Areas:  

Cancer

Anti-CD185/CXCR5 Antibody is an antibody inhibitor, targeting to human CD185/CXCR5.
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Cat. No.: HY-P991477

Target:  

CXCR

Research Areas:  

Inflammation/Immunology

HFB-100204 is a human monoclonal antibody (mAb) targeting CXCR5. HFB-100204 reduces CXCR5+ immune cells, including B cells and Tfh cells, in the blood and spleen of hCXCR5 knockout mice. HFB-100204 can be used in autoimmune diseases research .
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Cat. No.: HY-182774
CAS No.: 1092445-63-0
Target:  

CXCR

Research Areas:  

Cancer

YU241279 is an orally active CXCR5 inhibitor. YU241279 inhibits CXCL13-mediated Gαq-dependent calcium influx and Gαi2-dependent cAMP reduction in CXCR5-expressing cells. YU241279 inhibits the proliferation of CXCR5-expressing lymphoma cells. YU241279 reduces tumor burden in the peripheral blood and bone marrow of mice implanted with lymphoma tissues. YU241279 is well tolerated during oral administration in mice, maintains stable plasma drug concentrations, and shows no metabolic changes. YU241279 can be used in the research of angioimmunoblastic T-cell lymphoma and Burkitt B-cell lymphoma .
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Cat. No.: HY-P82361
Synonyms: cxcr5; BLR1; MDR15; C-X-C chemokine receptor type 5; CXC-R5; cxcr-5; Burkitt lymphoma receptor 1; Monocyte-derived receptor 15; MDR-15; CD185

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P84973
Synonyms: BLR1; MDR15; BLR 1 antibody; BLR1 antibody; Burkitt lymphoma receptor 1 antibody; Burkitt lymphoma receptor 1 GTP binding protein antibody; Burkitt lymphoma receptor 1; GTP binding protein; chemokine; C-X-C motif; receptor 5; antibody; C X C chemokine receptor type 5 antibody; C-X-C chemokine receptor type 5 antibody; CD 185 antibody; CD185 antibody; CD185 antigen antibody; Chemokine; C-X-C motif; receptor 5 antibody; Chemokine C X C motif receptor 5 antibody; Chemokine CXC motif receptor 5 antibody; Chemokine receptor 5 antibody; CXC chemokine receptor type 5 antibody; CXC R5 antibody; CXC-R5 antibody; cxcr 5 antibody; cxcr-5 antibody; cxcr5 antibody; cxcr5_HUMAN antibody; MDR 15 antibody; MDR-15 antibody; MDR15 antibody; MGC117347 antibody; Monocyte derived receptor 15 antibody; Monocyte-derived receptor 15 antibody;
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Cat. No.: HY-P85022
Synonyms: BLR1; MDR15; BLR 1 antibody; BLR1 antibody; Burkitt lymphoma receptor 1 antibody; Burkitt lymphoma receptor 1 GTP binding protein antibody; Burkitt lymphoma receptor 1; GTP binding protein; chemokine; C-X-C motif; receptor 5; antibody; C X C chemokine receptor type 5 antibody; C-X-C chemokine receptor type 5 antibody; CD 185 antibody; CD185 antibody; CD185 antigen antibody; Chemokine; C-X-C motif; receptor 5 antibody; Chemokine C X C motif receptor 5 antibody; Chemokine CXC motif receptor 5 antibody; Chemokine receptor 5 antibody; CXC chemokine receptor type 5 antibody; CXC R5 antibody; CXC-R5 antibody; cxcr 5 antibody; cxcr-5 antibody; cxcr5 antibody; cxcr5_HUMAN antibody; MDR 15 antibody; MDR-15 antibody; MDR15 antibody; MGC117347 antibody; Monocyte derived receptor 15 antibody; Monocyte-derived receptor 15 antibody;

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P704224
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: BLR1; L CD185; L MDR15; LC-X-C chemokine receptor type 5; LBurkitt lymphoma receptor 1; LMonocyte-derived receptor 15 (MDR-15)
Species:  
Source:  
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