Ipomoeassin F, a new cytotoxic macrocyclic glycoresin from the leaves of Ipomoea squamosa from the Suriname rainforest

  • Nat Prod Res. 2007 Aug;21(10):872-6. doi: 10.1080/14786410600929576.
Shugeng Cao  1 ,  Andrew Norris ,  Jan H Wisse ,  James S Miller ,  Randy Evans ,  David G I Kingston
Affiliations
  • 1. Department of Chemistry, Virginia Polytechnic Institute and State University, M/C 0212, Blacksburg, Virginia 24061, USA.
PMID: 17680496 DOI: 10.1080/14786410600929576
Abstract

A new cytotoxic macrocyclic glycoresin, ipomoeassin F (6), has been isolated from the leaves of Ipomoea squamosa. The structure was elucidated by the interpretation of spectral data. Compound 6 was strongly active in the A2780 (human ovarian Cancer cell line) assay with an IC(50) value of 0.036 microM.

Products