1 Result for "

1-Naphthohydroxamic acid

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1-Naphthohydroxamic acid" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-130538
CAS No.: 6953-61-3
Purity:  99.72%
Target:  

HDAC

Research Areas:  

Cancer

1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM. 1-Naphthohydroxamic acid is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity [2].1-Naphthohydroxamic acid can induce tubulin acetylation .
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