2 Results for "

10Panx

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "10Panx" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P1137
CAS No.: 955091-53-9
Target:  

Gap Junction Protein

Research Areas:  

Others

10Panx is a competitive inhibitor of selective Pannexin 1 (PANX1) channels. 10Panx blocks the opening of PANX1 channels, inhibits ATP release and downstream P2X7 receptor-mediated signaling pathways, thereby reducing cell death and inflammatory responses. 10Panx can be used in the study of diseases such as neuropathic pain, inflammatory bowel disease, and Clostridioides difficile infection. 10Panx can effectively reduce mechanical hyperalgesia and enhanced C-reflexes, and inhibit the expression of pro-inflammatory factors such as IL-6[1][2][3].
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Cat. No.: HY-P1138
CAS No.: 1315378-72-3
Synonyms: FSVYWAQADR
Target:  

Gap Junction Protein

Research Areas:  

Others

Scrambled 10Panx (FSVYWAQADR) is a random sequence variant of a specific inhibitory peptide 10Panx targeted at the half-channel of Pannexin-1 (Panx1). Scrambled 10Panx is used as a control peptide to determine whether other experimental conditions or peptides act through specific molecular mechanisms. Scrambled 10Panx can be used for research in neurobiology and cell biology .
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