3 Results for "

15917-65-4

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "15917-65-4" in MCE Product Catalog:

1
N-Desmethyltamoxifen hydrochloride
N-Desmethyltamoxifen hydrochloride
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1 Cited Publications
Cat. No.: HY-129099A
CAS No.: 15917-65-4
Purity:  99.93%
Category:  

Alkaloids Other Alkaloids Endogenous metabolite Disease Research Fields Cancer

Target:  

PKC Estrogen Receptor/ERR Drug Metabolite Endogenous Metabolite

N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation .
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N-Desmethyltamoxifen hydrochloride (Standard)
N-Desmethyltamoxifen hydrochloride (Standard)
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Cat. No.: HY-129099AR
CAS No.: 15917-65-4
Category:  

Alkaloids Other Alkaloids Endogenous metabolite

Target:  

Reference Standards PKC Estrogen Receptor/ERR Drug Metabolite Endogenous Metabolite

N-Desmethyltamoxifen (hydrochloride) (Standard) is the analytical standard of N-Desmethyltamoxifen (hydrochloride). This product is intended for research and analytical applications. N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation[1][2][3].
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1
N-Desmethyltamoxifen
N-Desmethyltamoxifen
0 Images
1 Cited Publications
Cat. No.: HY-129099
CAS No.: 31750-48-8
Category:  

Alkaloids Other Alkaloids Endogenous metabolite Disease Research Fields Cancer

Target:  

PKC Estrogen Receptor/ERR Drug Metabolite Endogenous Metabolite

N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation .
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