2 Results for "

192573-38-9

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "192573-38-9" in MCE Product Catalog:

Cat. No.: HY-125374A
CAS No.: 192573-38-9
Synonyms: XRP9881 dihydrate
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Larotaxel (dihydrate) (XRP9881 (dihydrate)), a new taxane compound prepared by partial synthesis from 10-deacetyl baccatin III, is active against tumors .
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Cat. No.: HY-125374
CAS No.: 156294-36-9
Purity:  ≥97.0%
Synonyms: XRP9881
Target:  

Apoptosis

Research Areas:  

Cancer

Larotaxel (XRP9881) is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel .
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