192573-38-9

Larotaxel dihydrate Chemical Structure
192573-38-9

Chemical Structure

Larotaxel dihydrate

Synonym(s): XRP9881 dihydrate

  • CAS No.: 192573-38-9
  • Formula:C45H57NO16
  • Molecular Weight:867.93

IUPAC Name: (1S,2S,4R,7R,8aR,9aS,10aR,12aS,12bR)-1-(benzoyloxy)-4-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-2-hydroxy-5,13,13-trimethyl-8-oxo-1,3,4,7,8,9,9a,10,10a,12b-decahydro-2H-2,6-methanocyclodeca[3,4]cyclopropa[4,5]benzo[1,2-b]oxete-7,12a(12H)-diyl diacetate dihydrate

InChIKey: SEFGUGYLLVNFIJ-HFHIORSXSA-N

SMILES: O=C([C@]1([H])OC(C)=O)[C@@]23[C@@]([C@@H]([C@@]4(O)C(C)(C)C1=C([C@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)C4)C)OC(C6=CC=CC=C6)=O)([H])[C@]7([C@@](OC7)([H])C[C@@H]2C3)OC(C)=O.O.O

Biological Activity: Larotaxel dihydrate (XRP9881 dihydrate) is an orally active and blood-brain barrier penetrant Microtubule stabilizer with an IC50 of 0.21 μM. Larotaxel dihydrate shows activity in Taxane-resistant tumor models. Larotaxel dihydrate exhibits antitumor activity in intracranial glioblastoma models. Larotaxel dihydrate can be used for research on advanced solid tumors[1][2].

Cat. No. Product Name Purity Description Pricing
HY-125374A 		Larotaxel dihydrate Larotaxel dihydrate (XRP9881 dihydrate) is an orally active and blood-brain barrier penetrant Microtubule stabilizer with an IC50 of 0.21 μM. Larotaxel dihydrate shows activity in Taxane-resistant tumor models. Larotaxel dihydrate exhibits antitumor activity in intracranial glioblastoma models. Larotaxel dihydrate can be used for research on advanced solid tumors.
Pricing 
Expand Hide
loading...
/
  • /
loading...
Size Price
Stock Quantity Availability Operate
/
In-stock
(Estimated to ship on )
(Estimated to ship TODAY)
Estimated to ship on
(Estimated to ship TODAY)

Amount:

USD 0.00

This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

Pricing 
Expand Hide

References

Keywords