1 Result for "

20-HEPE

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "20-HEPE" in MCE Product Catalog:

Cat. No.: HY-121888
CAS No.: 116477-57-7
Target:  

PPAR

Research Areas:  

Metabolic Disease

20-HEPE is a metabolite of eicosapentaenoic acid formed by ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. At 10 μM, it activates peroxisome proliferator-activated receptor α (PPARα) in COS-7 cells expressing a luciferase reporter gene. 20-HEPE also activates mouse transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks analgesic activity in rats.
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